{"id":1618,"date":"2025-04-23T15:11:00","date_gmt":"2025-04-23T15:11:00","guid":{"rendered":"https:\/\/dremrekaraagac.com\/?p=1618"},"modified":"2025-04-24T21:21:57","modified_gmt":"2025-04-24T21:21:57","slug":"yenidogan-kan-transfuzyon","status":"publish","type":"post","link":"https:\/\/dremrekaraagac.com\/?p=1618","title":{"rendered":"Yenido\u011fan Kan \u00dcr\u00fcn\u00fc Transf\u00fczyon Notlar\u0131"},"content":{"rendered":"

KAYNAK: TND 2021 KAN TRANSF\u00dcZYON REHBER\u0130<\/p>\n

YEN\u0130DO\u011eAN NORMAL HB DE\u011eERLER\u0130<\/span><\/p>\n

\"\"<\/p>\n

ER\u0130TROS\u0130T TRANSF\u00dcZYON SINIRLARI<\/span><\/p>\n

\"\"<\/p>\n

ER\u0130TROS\u0130 TRANSF\u00dcZYON M\u0130KTARI VE HIZI<\/span><\/p>\n

\"\"<\/p>\n

–>Eritrosit transf\u00fczyon esnas\u0131nda beslenmeye ara verilmesi \u00f6nerilir.<\/p>\n

–>Do\u011fum esnas\u0131nda yat\u0131\u015f kanlar\u0131n\u0131n bir k\u0131sm\u0131 kordun plesantal ucundan al\u0131nabilir.<\/p>\n

–>PREMAT\u00dcRELERDE en erken 2. haftada, ideali 6-8. haftada 3 mg\/kg\/g\u00fcn demir tedavisinin ba\u015flanarak 12-15. aya kadar buna devam edilmesi de transf\u00fczyon s\u0131kl\u0131\u011f\u0131n\u0131 azaltmaya yard\u0131mc\u0131 olacakt\u0131r<\/p>\n

–>Premat\u00fcre bebekler s\u0131k transf\u00fcze edildiklerinden serum ferritin d\u00fczeyleri aral\u0131kl\u0131 kontrol edilmelidir (Kan\u0131t
\nd\u00fczeyi 4)74,78,80-83. Ferritin > 300 \u03bcg\/L saptand\u0131\u011f\u0131nda, s\u00fcregelen enflamasyon yok ve y\u00fckseklik s\u0131k uygulanan
\ntransf\u00fczyona ba\u011fl\u0131 ise, DEM\u0130R tedavisine ara verilmeli, ferritin < 300 \u03bcg\/L oldu\u011funda tekrar ba\u015flanmal\u0131d\u0131r<\/p>\n

TROMBOS\u0130T TRANSF\u00dcZYON SINIRLARI<\/span><\/p>\n

\"\"<\/p>\n

–>Trombosit s\u00fcspansiyonu 10-15 ml\/kg dozunda, 5-10 mL\/kg\/saat h\u0131z\u0131nda 30-60 dakika i\u00e7inde uygulanmal\u0131d\u0131r.<\/p>\n

–>Her ne kadar trombosit s\u00fcspansiyonunun \u00e7alkalanmadan 8 saate kadar kullanu\u0131labilece\u011fi bildirilse de, genel \u00f6neri trombosit s\u00fcspansiyonunun \u00fcnitede dolapta saklanmamas\u0131 ve \u00fcniteye ula\u015f\u0131r ula\u015fmaz kullan\u0131lmas\u0131 y\u00f6n\u00fcndedir.<\/p>\n

GH G\u00d6RE PT APTT F\u0130BR\u0130NOJEN DE\u011eERLER\u0130<\/span><\/p>\n

\"\"<\/p>\n

TDP UYGULAMA END\u0130KASYONLARI<\/span><\/p>\n

\"\"<\/p>\n

–>Yenido\u011fanlarda TDP dozu en az 10-15 ml\/kg\u2019d\u0131r. Altta yatan tablonun ciddiyetine g\u00f6re >20 ml\/kg dozu ile
\nfakt\u00f6rlerin yar\u0131s\u0131 yerine konulur.<\/p>\n

–>Kriyopresipitat TDP\u2019den daha fazla fibrinojen, Fakt\u00f6r VIII, von Willebrand fakt\u00f6r, Fakt\u00f6r XIII ve fibronektin i\u00e7ermektedir ve asel\u00fcler bir kan \u00fcr\u00fcn\u00fc olarak kabul edilmektedir. Uyum testine gerek olmasa da, al\u0131c\u0131n\u0131n ABO kan grubuna uygun olmas\u0131 tercih edilir. eritildikten sonra oda \u0131s\u0131s\u0131nda hemen veya 6 saat i\u00e7inde transf\u00fczyon ger\u00e7ekle\u015ftirilmelidir.<\/p>\n

–>Kriyopresipitat esas olarak ciddi fibrinojen eksikli\u011fi, FXIII eksikli\u011fi ile ili\u015fkili kanama varl\u0131\u011f\u0131, karaci\u011fer disfonksiyonu ve kardiyak cerrahide endikedir.<\/p>\n

–>IVIG\u2019in neonatal alloimm\u00fcn trombositopeni tedavisinde 1g\/kg\/doz olarak 1-2 g\u00fcnde verilmesi \u00f6nerilmektedir. T\u00fcrk Neonatoloji Derne\u011fi Sar\u0131l\u0131k Rehberinde belirtildi\u011fi gibi Coombs (+) ABO veya RH uygunsuzlu\u011fu, subgrup uyu\u015fmazl\u0131klar\u0131, intrauterin transf\u00fczyon uygulanmas\u0131 gibi imm\u00fcn hemoliz-indirekt hiperbilir\u00fcbinemisi olan bebeklerde kan de\u011fi\u015fimi s\u0131n\u0131r\u0131na yak\u0131n bilir\u00fcbin d\u00fczeyleri varl\u0131\u011f\u0131nda IVIG kullan\u0131labilir<\/p>\n","protected":false},"excerpt":{"rendered":"

KAYNAK: TND 2021 KAN TRANSF\u00dcZYON REHBER\u0130 YEN\u0130DO\u011eAN NORMAL HB DE\u011eERLER\u0130 ER\u0130TROS\u0130T TRANSF\u00dcZYON SINIRLARI ER\u0130TROS\u0130 TRANSF\u00dcZYON M\u0130KTARI VE HIZI –>Eritrosit transf\u00fczyon esnas\u0131nda beslenmeye ara verilmesi \u00f6nerilir. –>Do\u011fum esnas\u0131nda yat\u0131\u015f kanlar\u0131n\u0131n bir k\u0131sm\u0131 kordun plesantal ucundan al\u0131nabilir. –>PREMAT\u00dcRELERDE en erken 2. haftada, ideali 6-8. haftada 3 mg\/kg\/g\u00fcn demir tedavisinin ba\u015flanarak 12-15. aya kadar buna devam edilmesi de… Daha fazlas\u0131n\u0131 oku »Yenido\u011fan Kan \u00dcr\u00fcn\u00fc Transf\u00fczyon Notlar\u0131<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":1634,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"off","neve_meta_content_width":70,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","footnotes":""},"categories":[32,14],"tags":[],"class_list":["post-1618","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kisa-notlar","category-saglik-profesyonelleri-icin"],"yoast_head":"\nYenido\u011fan Kan \u00dcr\u00fcn\u00fc Transf\u00fczyon Notlar\u0131 - Uzm. 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